Pub. Date : 2010 May
PMID : 20206278
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | In the current study, we investigated whether spermidine and polyamine antagonists that selectively block the NR2B subunit at the NMDAr alter the extinction of contextual conditioned fear in male Wistar rats. | Polyamines | glutamate ionotropic receptor NMDA type subunit 2B | Rattus norvegicus |
2 | These results suggest that exogenous and endogenous polyamines facilitate the extinction of contextual conditioned fear through activation of NR2B subunit-containing NMDAr in the hippocampus. | Polyamines | glutamate ionotropic receptor NMDA type subunit 2B | Rattus norvegicus |