Pub. Date : 2010 Jan
PMID : 20201778
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Aryl hydrocarbon receptor (AhR) ligands a-naphthoflavone (a-Naph), b-naphthoflavone (b-Naph) and 3-methylchloranthene (3-MC) increased UGT1A1 luciferase activity in a concentration dependent manner resulting in 17.2, 11.3 and 6.1 fold, respectively, at their highest concentrations, suggesting that endogenous AhR is also involved in the regulation of the UGT1A1 reporter construct in HepG2 cells. | Methylcholanthrene | UDP glucuronosyltransferase family 1 member A1 | Homo sapiens |
2 | Aryl hydrocarbon receptor (AhR) ligands a-naphthoflavone (a-Naph), b-naphthoflavone (b-Naph) and 3-methylchloranthene (3-MC) increased UGT1A1 luciferase activity in a concentration dependent manner resulting in 17.2, 11.3 and 6.1 fold, respectively, at their highest concentrations, suggesting that endogenous AhR is also involved in the regulation of the UGT1A1 reporter construct in HepG2 cells. | Methylcholanthrene | UDP glucuronosyltransferase family 1 member A1 | Homo sapiens |