Title : Glycerol-3-phosphate acyltransferase 1 deficiency in ob/ob mice diminishes hepatic steatosis but does not protect against insulin resistance or obesity.

Pub. Date : 2010 Jun

PMID : 20200319






2 Functional Relationships(s)
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1 In ob/ob mice, sterol regulatory element binding protein 1 (SREBP1) mediates the induction of steatosis by upregulating target genes, including glycerol-3-phosphate acyltransferase-1 (Gpat1), which catalyzes the first and committed step in the pathway of glycerolipid synthesis. glycerolipid glycerol-3-phosphate acyltransferase, mitochondrial Mus musculus
2 In ob/ob mice, sterol regulatory element binding protein 1 (SREBP1) mediates the induction of steatosis by upregulating target genes, including glycerol-3-phosphate acyltransferase-1 (Gpat1), which catalyzes the first and committed step in the pathway of glycerolipid synthesis. glycerolipid glycerol-3-phosphate acyltransferase, mitochondrial Mus musculus