Pub. Date : 2010 Jun
PMID : 20200117
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The decline in AIMs with combined nicotine and mecamylamine treatment was not additive, suggesting that nicotine exerts its effects via a nAChR interaction. | Nicotine | cholinergic receptor nicotinic beta 1 subunit | Rattus norvegicus |
| 2 | The decline in AIMs with combined nicotine and mecamylamine treatment was not additive, suggesting that nicotine exerts its effects via a nAChR interaction. | Nicotine | cholinergic receptor nicotinic beta 1 subunit | Rattus norvegicus |
| 3 | This latter finding, combined with data showing that mecamylamine reduced AIMs to a similar extent as nicotine, and that nicotine or mecamylamine treatment both decreased alpha6beta2* and increased alpha4beta2* nAChR expression, suggests that the nicotine-mediated improvement in L-DOPA-induced AIMs may involve a desensitization block. | Nicotine | cholinergic receptor nicotinic beta 1 subunit | Rattus norvegicus |
| 4 | This latter finding, combined with data showing that mecamylamine reduced AIMs to a similar extent as nicotine, and that nicotine or mecamylamine treatment both decreased alpha6beta2* and increased alpha4beta2* nAChR expression, suggests that the nicotine-mediated improvement in L-DOPA-induced AIMs may involve a desensitization block. | Nicotine | cholinergic receptor nicotinic beta 1 subunit | Rattus norvegicus |