Title : Single cell endocrinology: analysis of P-450scc activity by fluorescence detection methods.

Pub. Date : 1991 May

PMID : 2019272






1 Functional Relationships(s)
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1 A mechanism-based, fluorogenic probe for the cytochrome P-450scc (cholesterol side chain cleavage) enzyme, rate-limiting for the conversion of cholesterol to steroid hormones, is introduced and its application to the study of enzyme activity and regulation in single steroidogenic cells by several fluorescence detection methods is demonstrated. Steroids cytochrome P450 family 11 subfamily A member 1 Homo sapiens