Title : Truncated fluorocyclopentenyl pyrimidines as S-adenosylhomocysteine hydrolase inhibitors.

Pub. Date : 2009 May

PMID : 20183604






2 Functional Relationships(s)
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1 On the basis of inhibitory activity of truncated cyclopentenyl cytosine against S-adenosylhomocysteine hydrolase (SAH), its fluorocyclopentenyl pyrimidine derivatives were efficiently synthesized from D-ribose via electrophilic fluorination as a key step. Ribose adenosylhomocysteinase Homo sapiens
2 On the basis of inhibitory activity of truncated cyclopentenyl cytosine against S-adenosylhomocysteine hydrolase (SAH), its fluorocyclopentenyl pyrimidine derivatives were efficiently synthesized from D-ribose via electrophilic fluorination as a key step. Ribose adenosylhomocysteinase Homo sapiens