Title : An evaluation of the cytochrome P450 inhibition potential of selected pesticides in human hepatic microsomes.

Pub. Date : 2009 Aug

PMID : 20183062






1 Functional Relationships(s)
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1 Deltamethrin and fenvalerate were potent inhibitors of CYP2D6 (IC(50) values of approximately 3 micro M) while lambda-cyhalothrin potently inhibited both CYP2D6 and CYP3A4-mediated activities (IC(50)"s about 3-4 micro M). decamethrin cytochrome P450 family 2 subfamily D member 6 Homo sapiens