Pub. Date : 2010 Jul
PMID : 20179743
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The inhibition of mevalonate pathway induces upregulation of NALP3 expression: new insight in the pathogenesis of mevalonate kinase deficiency. | Mevalonic Acid | NLR family pyrin domain containing 3 | Homo sapiens |
| 2 | Our results, although preliminary, showed that the inhibition of the mevalonate pathway led to a hyper-expression of NALP3, suggesting a possible involvement of NALP3-inflammasome in the activation of caspase-1 consequent to GGPP decrement. | Mevalonic Acid | NLR family pyrin domain containing 3 | Homo sapiens |
| 3 | Our results, although preliminary, showed that the inhibition of the mevalonate pathway led to a hyper-expression of NALP3, suggesting a possible involvement of NALP3-inflammasome in the activation of caspase-1 consequent to GGPP decrement. | Mevalonic Acid | NLR family pyrin domain containing 3 | Homo sapiens |