Pub. Date : 2010 Feb 19
PMID : 20174566
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | To identify predictors of pathogenic mutation status in familial breast cancer patients, we explored the use of gene expression arrays to assess the effect of two DNA-damaging agents (irradiation and mitomycin C) on cellular response in relation to BRCA1 and BRCA2 mutation status. | Mitomycin | BRCA2 DNA repair associated | Homo sapiens |
2 | Using an RNA-pooling strategy, we found that treating LCLs with 1.2 microM mitomycin C and measuring the gene expression profiles 1 hour post-treatment had the greatest potential to discriminate BRCA1, BRCA2, and BRCAX mutation status. | Mitomycin | BRCA2 DNA repair associated | Homo sapiens |