Pub. Date : 2010 Jun 1
PMID : 20170694
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Here, we evaluated the in vivo delivery of siRNAs conjugated with different linkers to cholesterol by targeting CNPase (2"-3"-cyclic nucleotide 3"-phosphodiesterase) in oligodendrocytes. | Cholesterol | 2',3'-cyclic nucleotide 3' phosphodiesterase | Rattus norvegicus |
| 2 | Here, we evaluated the in vivo delivery of siRNAs conjugated with different linkers to cholesterol by targeting CNPase (2"-3"-cyclic nucleotide 3"-phosphodiesterase) in oligodendrocytes. | Cholesterol | 2',3'-cyclic nucleotide 3' phosphodiesterase | Rattus norvegicus |
| 3 | Furthermore, conjugation of siRNA to cholesterol with a cleavable disulfide linker appears to be beneficial for improving the potency of silencing of CNPase mRNA in oligodendrocytes in vivo. | Cholesterol | 2',3'-cyclic nucleotide 3' phosphodiesterase | Rattus norvegicus |