Title : Hippocampal neurons exposed to the environmental contaminants methylmercury and polychlorinated biphenyls undergo cell death via parallel activation of calpains and lysosomal proteases.

Pub. Date : 2011 Jan

PMID : 20169435






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Accordingly, pre-treatment with the calpain specific inhibitor PD150606 and/or the cathepsin D inhibitor Pepstatin protected against the cytotoxicity of MeHg and PCBs, and the protection was significantly enhanced when the two inhibitors were combined. pepstatin cathepsin D Mus musculus