Title : Celastrol suppresses angiogenesis-mediated tumor growth through inhibition of AKT/mammalian target of rapamycin pathway.

Pub. Date : 2010 Mar 1

PMID : 20160026






2 Functional Relationships(s)
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1 Furthermore, Celastrol abrogated VEGF-induced sprouting of the vessels from aortic rings and inhibited vascular formation in the Matrigel plug assay in vivo. celastrol vascular endothelial growth factor A Homo sapiens
2 Celastrol suppressed the VEGF-induced activation of AKT, mammalian target of rapamycin (mTOR), and ribosomal protein S6 kinase (P70S6K). celastrol vascular endothelial growth factor A Homo sapiens