Title : Para-phenylenediamine induced DNA damage and apoptosis through oxidative stress and enhanced caspase-8 and -9 activities in Mardin-Darby canine kidney cells.

Pub. Date : 2010 Jun

PMID : 20156547






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Para-phenylenediamine induced DNA damage and apoptosis through oxidative stress and enhanced caspase-8 and -9 activities in Mardin-Darby canine kidney cells. 4-phenylenediamine caspase 8 Canis lupus familiaris
2 Furthermore, p-PD induced apoptosis through activated initiator caspase-8 and -9, and effector caspase-3/7. 4-phenylenediamine caspase 8 Canis lupus familiaris
3 Based on these results, we suggested that p-PD induce apoptosis which was mediated with caspase-8, caspase-9 and caspase-3/7 activation via the involvement of ROS. 4-phenylenediamine caspase 8 Canis lupus familiaris