Title : Processing of meiotic DNA double strand breaks requires cyclin-dependent kinase and multiple nucleases.

Pub. Date : 2010 Apr 9

PMID : 20150422






1 Functional Relationships(s)
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1 Here, we demonstrate that phosphorylation of Sae2 Ser-267 by cyclin-dependent kinase 1 (Cdk1) is required to initiate meiotic DSB resection by allowing Spo11 removal from DSB ends. Serine DNA topoisomerase (ATP-hydrolyzing) Saccharomyces cerevisiae S288C