Pub. Date : 2010 Jun
PMID : 20148354
11 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Suppression of the androgen receptor function by quercetin through protein-protein interactions of Sp1, c-Jun, and the androgen receptor in human prostate cancer cells. | Quercetin | androgen receptor | Homo sapiens |
2 | Suppression of the androgen receptor function by quercetin through protein-protein interactions of Sp1, c-Jun, and the androgen receptor in human prostate cancer cells. | Quercetin | androgen receptor | Homo sapiens |
3 | We have previously reported that the increase in c-Jun expression induced by quercetin inhibited androgen receptor (AR) transactivation, and Sp1 was involved in quercetin-mediated downregulation of AR activity. | Quercetin | androgen receptor | Homo sapiens |
4 | We have previously reported that the increase in c-Jun expression induced by quercetin inhibited androgen receptor (AR) transactivation, and Sp1 was involved in quercetin-mediated downregulation of AR activity. | Quercetin | androgen receptor | Homo sapiens |
5 | We have previously reported that the increase in c-Jun expression induced by quercetin inhibited androgen receptor (AR) transactivation, and Sp1 was involved in quercetin-mediated downregulation of AR activity. | Quercetin | androgen receptor | Homo sapiens |
6 | The physical associations of c-Jun, Sp1, and AR induced by quercetin were further demonstrated by co-immunoprecipitation experiments. | Quercetin | androgen receptor | Homo sapiens |
7 | In addition, quercetin-mediated repression of AR expression and activity was partially reversed by blocking of JNK signaling pathway. | Quercetin | androgen receptor | Homo sapiens |
8 | These results suggested that c-Jun might play an important role in the suppression of AR expression and activity in the presence of quercetin, and association of a c-Jun/Sp1/AR protein complex induced by quercetin represented a novel mechanism that was involved in down-regulation of the AR function in prostate cancer cells. | Quercetin | androgen receptor | Homo sapiens |
9 | These results suggested that c-Jun might play an important role in the suppression of AR expression and activity in the presence of quercetin, and association of a c-Jun/Sp1/AR protein complex induced by quercetin represented a novel mechanism that was involved in down-regulation of the AR function in prostate cancer cells. | Quercetin | androgen receptor | Homo sapiens |
10 | These results suggested that c-Jun might play an important role in the suppression of AR expression and activity in the presence of quercetin, and association of a c-Jun/Sp1/AR protein complex induced by quercetin represented a novel mechanism that was involved in down-regulation of the AR function in prostate cancer cells. | Quercetin | androgen receptor | Homo sapiens |
11 | These results suggested that c-Jun might play an important role in the suppression of AR expression and activity in the presence of quercetin, and association of a c-Jun/Sp1/AR protein complex induced by quercetin represented a novel mechanism that was involved in down-regulation of the AR function in prostate cancer cells. | Quercetin | androgen receptor | Homo sapiens |