Pub. Date : 2010 Apr
PMID : 20146252
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Ursolic acid induces PC-3 cell apoptosis via activation of JNK and inhibition of Akt pathways in vitro. | ursolic acid | AKT serine/threonine kinase 1 | Homo sapiens |
| 2 | On the other hand, UA inhibited the Akt pathway, subsequently upregulating the expression of Fas ligand (FasL), which initiates death receptor-mediated apoptosis in PC-3 cells. | ursolic acid | AKT serine/threonine kinase 1 | Homo sapiens |
| 3 | UA also inhibited cell invasion by downregulating matrix metalloproteinase-9 via inhibition of Akt in PC-3 cells. | ursolic acid | AKT serine/threonine kinase 1 | Homo sapiens |