Title : Synthesis of physostigmine analogues and evaluation of their anticholinesterase activities.

Pub. Date : 2010 Mar 1

PMID : 20144867






1 Functional Relationships(s)
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1 Most of them showed potent inhibition activities against AChE, in which compound 17 especially exhibited significantly higher selectivity over BChE than phenserine, a compound currently on clinical trial. phenserine acetylcholinesterase (Cartwright blood group) Homo sapiens