Title : Effect of chronic treatment with Rosiglitazone on Leydig cell steroidogenesis in rats: in vivo and ex vivo studies.

Pub. Date : 2010 Feb 9

PMID : 20144211






1 Functional Relationships(s)
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1 Testosterone production was induced either by activators of the cAMP/PKA pathway (hCG and dbcAMP) or substrates of steroidogenesis [22(R)-hydroxy-cholesterol (22(R)-OH-C), which is a substrate for the P450scc enzyme, and pregnenolone, which is the product of the P450scc-catalyzed step]. Cyclic AMP hypertrichosis 2 (generalised, congenital) Homo sapiens