Title : VAV2 and VAV3 as candidate disease genes for spontaneous glaucoma in mice and humans.

Pub. Date : 2010 Feb 4

PMID : 20140222






1 Functional Relationships(s)
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1 METHODOLOGY/PRINCIPAL FINDINGS: Here we demonstrate that deficiency of Vav2 and Vav3, guanine nucleotides exchange factors for Rho guanosine triphosphatases, leads to an ocular phenotype similar to human glaucoma. Guanine Nucleotides vav guanine nucleotide exchange factor 2 Homo sapiens