Title : Benzyl isothiocyanate (BITC) inhibits migration and invasion of human colon cancer HT29 cells by inhibiting matrix metalloproteinase-2/-9 and urokinase plasminogen (uPA) through PKC and MAPK signaling pathway.

Pub. Date : 2010 Mar 10

PMID : 20136087






3 Functional Relationships(s)
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1 Benzyl isothiocyanate (BITC) inhibits migration and invasion of human colon cancer HT29 cells by inhibiting matrix metalloproteinase-2/-9 and urokinase plasminogen (uPA) through PKC and MAPK signaling pathway. benzyl isothiocyanate matrix metallopeptidase 2 Homo sapiens
2 Benzyl isothiocyanate (BITC) inhibits migration and invasion of human colon cancer HT29 cells by inhibiting matrix metalloproteinase-2/-9 and urokinase plasminogen (uPA) through PKC and MAPK signaling pathway. benzyl isothiocyanate matrix metallopeptidase 2 Homo sapiens
3 Reductions in the enzyme activity, protein and mRNA (mRNA) levels of MMP-2 were observed in BITC-treated HT29 cells. benzyl isothiocyanate matrix metallopeptidase 2 Homo sapiens