Title : Challenges of steroid biotransformation with human cytochrome P450 monooxygenase CYP21 using resting cells of recombinant Schizosaccharomyces pombe.

Pub. Date : 2010 Apr 15

PMID : 20132843






1 Functional Relationships(s)
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1 To identify the limiting factors in a P450 catalyzed whole cell biotransformation, 21-hydroxylation of 17-alpha-hydroxyprogesterone in Schizosaccharomyces pombe expressing human CYP21 was chosen as model reaction. 17-alpha-Hydroxyprogesterone cytochrome P450 family 21 subfamily A member 2 Homo sapiens