Title : SZ-685C, a marine anthraquinone, is a potent inducer of apoptosis with anticancer activity by suppression of the Akt/FOXO pathway.

Pub. Date : 2010 Feb 1

PMID : 20128807






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 SZ-685C had a direct apoptosis-inducing effect through both the extrinsic and intrinsic apoptotic pathways, as shown by activation of caspase-8 and 9 as well as effector caspase-3 and poly (ADP-ribose) polymerase. SZ 685C caspase 3 Homo sapiens