Title : Epigenetically regulated clonal heritability of CTA expression profiles in human melanoma.

Pub. Date : 2010 May

PMID : 20127705






3 Functional Relationships(s)
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Protein Name
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1 Treatment of clone 5(M3-low) with a DNA hypomethylating agent (DHA) resulted in an up-regulated expression of MAGE-A3, which was inherited at single cell level, being still detectable at day 60 in its sub-clones. Dihydroalprenolol MAGE family member A3 Homo sapiens
2 Bisulfite sequencing demonstrated that also MAGE-A3 promoter methylation status was inherited among sub-clones generated from DHA-treated clone 5(M3-low) and strictly correlated with MAGE-A3 expression levels in investigated sub-clones. Dihydroalprenolol MAGE family member A3 Homo sapiens
3 Bisulfite sequencing demonstrated that also MAGE-A3 promoter methylation status was inherited among sub-clones generated from DHA-treated clone 5(M3-low) and strictly correlated with MAGE-A3 expression levels in investigated sub-clones. Dihydroalprenolol MAGE family member A3 Homo sapiens