Pub. Date : 2010 Apr
PMID : 20125033
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | L-arginine enhances nitrative stress and exacerbates tumor necrosis factor-alpha toxicity to human endothelial cells in culture: prevention by propofol. | Arginine | tumor necrosis factor | Homo sapiens |
| 2 | We postulated that L-arginine may exacerbate TNF-induced endothelial cell apoptosis by enhancing peroxynitrite-mediated nitrative stress. | Arginine | tumor necrosis factor | Homo sapiens |
| 3 | L-arginine did not enhance TNF-induced increases of superoxide and peroxynitrite production but further increased TNF-induced increase of nitrotyrosine production and exacerbated TNF-mediated cell apoptosis. | Arginine | tumor necrosis factor | Homo sapiens |
| 4 | L-arginine did not enhance TNF-induced increases of superoxide and peroxynitrite production but further increased TNF-induced increase of nitrotyrosine production and exacerbated TNF-mediated cell apoptosis. | Arginine | tumor necrosis factor | Homo sapiens |
| 5 | Thus, under pathological conditions associated with increased TNF production, L-arginine supplementation may further exacerbate TNF cellular toxicity by enhancing nitrative stress. | Arginine | tumor necrosis factor | Homo sapiens |
| 6 | Thus, under pathological conditions associated with increased TNF production, L-arginine supplementation may further exacerbate TNF cellular toxicity by enhancing nitrative stress. | Arginine | tumor necrosis factor | Homo sapiens |