Pub. Date : 2010 Apr
PMID : 20123963
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | To elucidate the direct phosphorylation of p53 at Ser46 by ATM, an ATM mutant (ATM-AS) sensitive to ATP analogues was engineered. | Adenosine Triphosphate | tumor protein p53 | Homo sapiens |
| 2 | In vitro kinase assays revealed that p53 was phosphorylated at Ser46 by ATM-AS, even when ATP analogues were used as phosphate donors, although this phosphorylation site is not in an SQ motif, a consensus ATM site. | Adenosine Triphosphate | tumor protein p53 | Homo sapiens |