Title : Glycine transporter GLYT1 is essential for glycine-mediated protection of human intestinal epithelial cells against oxidative damage.

Pub. Date : 2010 Mar 15

PMID : 20123783






4 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Glycine transporter GLYT1 is essential for glycine-mediated protection of human intestinal epithelial cells against oxidative damage. Glycine solute carrier family 6 member 9 Homo sapiens
2 The objectives of the current study were to demonstrate directly glycine-mediated protection of human intestinal epithelial cells and to determine the requirement for glycine uptake by the specific transporter GLYT1. Glycine solute carrier family 6 member 9 Homo sapiens
3 Protection was dependent on GLYT1 activity, being blocked by a specific GLYT1 inhibitor, supporting a requirement for intracellular glycine accumulation. Glycine solute carrier family 6 member 9 Homo sapiens
4 Protection was dependent on GLYT1 activity, being blocked by a specific GLYT1 inhibitor, supporting a requirement for intracellular glycine accumulation. Glycine solute carrier family 6 member 9 Homo sapiens