Title : The TEA transcription factor Tec1 confers promoter-specific gene regulation by Ste12-dependent and -independent mechanisms.

Pub. Date : 2010 Apr

PMID : 20118212






3 Functional Relationships(s)
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1 Here, we show that in vivo, physiological amounts of Tec1 are sufficient to stimulate TCS-mediated gene expression and transcription of the FLO11 gene in the absence of Ste12. 9-ethyl-N-(3,4,5-trimethoxyphenyl)carbazole-3-sulfonamide Tec1p Saccharomyces cerevisiae S288C
2 In vitro, Tec1 is able to bind TCS elements with high affinity and specificity without Ste12. 9-ethyl-N-(3,4,5-trimethoxyphenyl)carbazole-3-sulfonamide Tec1p Saccharomyces cerevisiae S288C
3 Our study suggests that Tec1 is able to regulate TCS-mediated gene expression by Ste12-dependent and Ste12-independent mechanisms that enable promoter-specific transcriptional control. 9-ethyl-N-(3,4,5-trimethoxyphenyl)carbazole-3-sulfonamide Tec1p Saccharomyces cerevisiae S288C