Title : Cortical regulation of striatal medium spiny neuron dendritic remodeling in parkinsonism: modulation of glutamate release reverses dopamine depletion-induced dendritic spine loss.

Pub. Date : 2010 Oct

PMID : 20118184






1 Functional Relationships(s)
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1 Treatment of the cultures with the mGluR2/3 agonist LY379268 to suppress corticostriatal glutamate release completely blocked spine loss in dopamine-denervated cultures. Dopamine glutamate receptor, ionotropic, AMPA2 (alpha 2) Mus musculus