Title : Down-regulation of Notch1 by gamma-secretase inhibition contributes to cell growth inhibition and apoptosis in ovarian cancer cells A2780.

Pub. Date : 2010 Feb 26

PMID : 20117093






1 Functional Relationships(s)
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1 Down-regulation of Notch1 expression by DAPT was able to substantially inhibit cell growth, induce G1 cell cycle arrest and induce cell apoptosis in A2780 in dose- and time-dependent manner. dapt notch receptor 1 Homo sapiens