Title : Phase I trial of non-cytotoxic suramin as a modulator of docetaxel and gemcitabine therapy in previously treated patients with non-small cell lung cancer.

Pub. Date : 2010 Nov

PMID : 20107799






2 Functional Relationships(s)
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1 PURPOSE: In preclinical models, non-cytotoxic suramin (concentrations <50 muM) potentiates the activity of multiple chemotherapeutic agents. Suramin latexin Homo sapiens
2 The target plasma suramin concentration range of 10-50 muM was achieved in 90% of treatments. Suramin latexin Homo sapiens