Title : Spotlight on memantine in moderate to severe Alzheimer's disease.

Pub. Date : 2010 Feb 1

PMID : 20104942






2 Functional Relationships(s)
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1 Memantine has a distinct mode of action compared with that of acetylcholinesterase (AChE) inhibitors, and in a well designed study, combination therapy with memantine plus donepezil improved outcomes more than donepezil plus placebo in all four domains (function, cognition, behaviour and global change). Memantine acetylcholinesterase (Cartwright blood group) Homo sapiens
2 Memantine has a distinct mode of action compared with that of acetylcholinesterase (AChE) inhibitors, and in a well designed study, combination therapy with memantine plus donepezil improved outcomes more than donepezil plus placebo in all four domains (function, cognition, behaviour and global change). Memantine acetylcholinesterase (Cartwright blood group) Homo sapiens