Title : Radiosensitization of epidermal growth factor receptor/HER2-positive pancreatic cancer is mediated by inhibition of Akt independent of ras mutational status.

Pub. Date : 2010 Feb 1

PMID : 20103665






1 Functional Relationships(s)
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Protein Name
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1 Overexpression of constitutively active K-ras (G12V) abrogated lapatinib-mediated inhibition of both Akt phosphorylation and radiosensitization. Lapatinib AKT serine/threonine kinase 1 Homo sapiens