Pub. Date : 2009 Nov
PMID : 20101991
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | To investigate the affinity constants of heparin with high mobility group protein 1(HMGB1) and HMGB1 with the receptor of advanced glycation end products (RAGE) and to analyze the impact of heparin on the affinity of HMGB1 and RAGE, the standard BIAcore amine coupling chemistry protocol using EDC and NHS was employed for immobilizing. | Heparin | long intergenic non-protein coding RNA 914 | Homo sapiens |
| 2 | To investigate the affinity constants of heparin with high mobility group protein 1(HMGB1) and HMGB1 with the receptor of advanced glycation end products (RAGE) and to analyze the impact of heparin on the affinity of HMGB1 and RAGE, the standard BIAcore amine coupling chemistry protocol using EDC and NHS was employed for immobilizing. | Heparin | long intergenic non-protein coding RNA 914 | Homo sapiens |
| 3 | Binding analysis was used to investigate the impact of heparin on the affinity of HMGB1 and RAGE. | Heparin | long intergenic non-protein coding RNA 914 | Homo sapiens |
| 4 | After 50 mg x L(-1) of HMGB1 was mixed with heparin of 50, 100, 1 000, 10 000 u x L(-1), the combining amount of HMGB1 and RAGE declined from 100 to 50 RU. | Heparin | long intergenic non-protein coding RNA 914 | Homo sapiens |
| 5 | It was concluded that heparin can combine with HMGB1 and affect the affinity of HMGB1/RAGE. | Heparin | long intergenic non-protein coding RNA 914 | Homo sapiens |