Pub. Date : 2010 Apr
PMID : 20086155
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Neutrophil gelatinase-associated lipocalin expresses antimicrobial activity by interfering with L-norepinephrine-mediated bacterial iron acquisition. | Iron | lipocalin 2 | Homo sapiens |
2 | Iron complexes of NE resemble those of bacterial siderophores that are scavenged by human neutrophil gelatinase-associated lipocalin (NGAL) as part of the innate immune defense. | Iron | lipocalin 2 | Homo sapiens |
3 | Iron complexes of NE resemble those of bacterial siderophores that are scavenged by human neutrophil gelatinase-associated lipocalin (NGAL) as part of the innate immune defense. | Iron | lipocalin 2 | Homo sapiens |
4 | Here, we show that NGAL binds iron-complexed NE, indicating physiological relevance for both bacterial and human iron metabolism. | Iron | lipocalin 2 | Homo sapiens |
5 | Here, we show that NGAL binds iron-complexed NE, indicating physiological relevance for both bacterial and human iron metabolism. | Iron | lipocalin 2 | Homo sapiens |
6 | This study demonstrates for the first time that human NGAL not only neutralizes pathogen-derived virulence factors but also can effectively scavenge an iron-chelate complex abundant in the host. | Iron | lipocalin 2 | Homo sapiens |