Title : Uncoupled cardiac nitric oxide synthase mediates diastolic dysfunction.

Pub. Date : 2010 Feb 2

PMID : 20083682






1 Functional Relationships(s)
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Protein Name
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1 Hypertension can lead to a reduction in vascular NO, in part because NO synthase (NOS) becomes uncoupled when oxidative depletion of its cofactor tetrahydrobiopterin (BH(4)) occurs. sapropterin nitric oxide synthase 1, neuronal Mus musculus