Title : Insufficiency of Janus kinase 2-autonomous leptin receptor signals for most physiologic leptin actions.

Pub. Date : 2010 Apr

PMID : 20068132






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Leptin binding to LepRb initiates signaling by activating the associated Janus kinase 2 (Jak2) tyrosine kinase, which promotes the phosphorylation of tyrosine residues on the intracellular tail of LepRb. Tyrosine leptin Mus musculus