Title : Alterations in brain cholesterol metabolism in the APPSLxPS1mut mouse, a model for Alzheimer's disease.

Pub. Date : 2010

PMID : 20061631






1 Functional Relationships(s)
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1 In line with the fact that desmosterol and 24(S)-OHcholesterol are Liver X Receptor (LXR) activators, the LXR-target genes Abca1 and Apoc1 were upregulated predominantly in hippocampus of APPSLxPS1mut mice at both ages evaluated. 24(s)-ohcholesterol apolipoprotein C-I Mus musculus