Pub. Date : 2010 Mar
PMID : 20043933
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In contrast, daidzein was 1000 times more powerful in stimulating ERbeta- over ERalpha-mediated transactivation. | daidzein | estrogen receptor 2 | Gallus gallus |
| 2 | Daidzein, in concentrations ranging from 5 nM to 50 microM, did not affect ERbeta-mediated transactivation induced by 1 nM E(2), but it significantly inhibited ERbeta-mediated transactivation induced by 10 nM E(2) at 500 nM. | daidzein | estrogen receptor 2 | Gallus gallus |
| 3 | Despite the tremendous difference in sensitivity between the two in vitro systems, daidzein exhibited greater potency as an estrogen-antagonist for ERbeta-mediated activity. | daidzein | estrogen receptor 2 | Gallus gallus |