Title : Reduced cell death, invasive and angiogenic features conferred by BRCA1-deficiency in mammary epithelial cells transformed with H-Ras.

Pub. Date : 2009 Dec

PMID : 20038817






1 Functional Relationships(s)
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1 Our results suggest that loss of BRCA1 function may contribute to the aggressiveness of Ras-MAPK driven human breast cancer with associated increase in levels of cyclin D1 and c-myc, enhanced MAPK activity, angiogenic potential & invasiveness. Adenosine Monophosphate BRCA1 DNA repair associated Homo sapiens