Pub. Date : 2010 Jan
PMID : 20037601
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Effect of betulinic acid on the regulation of Hiwi and cyclin B1 in human gastric adenocarcinoma AGS cells. | betulinic acid | cyclin B1 | Homo sapiens |
| 2 | The expression of Hiwi and Cyclin B1 was down-regulated in BA-treated AGS cells in a dose-dependent manner. | betulinic acid | cyclin B1 | Homo sapiens |
| 3 | CONCLUSION: BA exerted potent effect on growth inhibition, G(2)/M cell cycle arrest and induction of apoptosis in AGS cells in vitro, possibly associated with the down-regulation of Hiwi and its downstream target Cyclin B1 expression. | betulinic acid | cyclin B1 | Homo sapiens |