Pub. Date : 2010 Mar 5
PMID : 20036641
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Here, we report that GABA(B1), via the coiled-coil domain, can also bind to soluble proteins of unknown function, that are affected in 22q11 deletion/DiGeorge syndrome and are therefore referred to as DiGeorge critical region 6 (DGCR6). | gamma-Aminobutyric Acid | DiGeorge syndrome critical region gene 6 | Homo sapiens |
| 2 | Here, we report that GABA(B1), via the coiled-coil domain, can also bind to soluble proteins of unknown function, that are affected in 22q11 deletion/DiGeorge syndrome and are therefore referred to as DiGeorge critical region 6 (DGCR6). | gamma-Aminobutyric Acid | DiGeorge syndrome critical region gene 6 | Homo sapiens |
| 3 | In transfected neurons the GABA(B1)-DGCR6 association resulted in a redistribution of both proteins into intracellular clusters. | gamma-Aminobutyric Acid | DiGeorge syndrome critical region gene 6 | Homo sapiens |
| 4 | Furthermore, the C-terminus of GABA(B2) interfered with the novel interaction, consistent with heterodimer formation overriding transient DGCR6-binding to GABA(B1). | gamma-Aminobutyric Acid | DiGeorge syndrome critical region gene 6 | Homo sapiens |
| 5 | Furthermore, the C-terminus of GABA(B2) interfered with the novel interaction, consistent with heterodimer formation overriding transient DGCR6-binding to GABA(B1). | gamma-Aminobutyric Acid | DiGeorge syndrome critical region gene 6 | Homo sapiens |