Title : Cell death induced by novel fluorinated taxanes in drug-sensitive and drug-resistant cancer cells.

Pub. Date : 2011 Jun

PMID : 20013348






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Selected fluorinated taxanes, SB-T-12853 and SB-T-12854, at the death-inducing concentrations (30 nM for MDA-MB-435 and 300 nM for NCI/ADR-RES) were shown to activate significantly caspase-3, caspase-9, caspase-2 and also slightly caspase-8. fluorinated taxanes caspase 2 Homo sapiens