Pub. Date : 2009 Dec 14
PMID : 20008566
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Using Osh4p/Kes1p as a representative ORP, we show that ORPs have at least two membrane-binding surfaces; one near the mouth of the sterol-binding pocket and a distal site that can bind a second membrane. | Sterols | oxysterol-binding protein KES1 | Saccharomyces cerevisiae S288C |
| 2 | Using Osh4p/Kes1p as a representative ORP, we show that ORPs have at least two membrane-binding surfaces; one near the mouth of the sterol-binding pocket and a distal site that can bind a second membrane. | Sterols | oxysterol-binding protein KES1 | Saccharomyces cerevisiae S288C |
| 3 | The distal site is required for the protein to function in cells and, remarkably, regulates the rate at which Osh4p extracts and delivers sterols in a phosphoinositide-dependent manner. | Sterols | oxysterol-binding protein KES1 | Saccharomyces cerevisiae S288C |