Title : Identification of human UGT2B7 as the major isoform involved in the O-glucuronidation of chloramphenicol.

Pub. Date : 2010 Mar

PMID : 20008037






1 Functional Relationships(s)
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Protein Name
Organism
1 Reaction phenotyping for the glucuronidation of CP with 12 expressed human liver UGT isoforms has identified UGT2B7 as having the highest activity for 3-O- and 1-O-CP glucuronidation with minor contributions from UGT1A6 and UGT1A9. 1-hexadecyl-2-acetyl-glycero-3-phosphocholine UDP glucuronosyltransferase family 1 member A complex locus Homo sapiens