Pub. Date : 2010 Mar
PMID : 20007406
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Celastrol, isolated from a Chinese medicinal herb, is a novel heat shock protein 90 (Hsp90) inhibitor with potent anticancer activity against glioma in vitro and in vivo. | celastrol | heat shock protein 90 alpha family class A member 1 | Homo sapiens |
2 | Celastrol, isolated from a Chinese medicinal herb, is a novel heat shock protein 90 (Hsp90) inhibitor with potent anticancer activity against glioma in vitro and in vivo. | celastrol | heat shock protein 90 alpha family class A member 1 | Homo sapiens |
3 | Combined treatment of glioma cells with sulfasalazine and celastrol led to chemosensitization, as suggested by increased celastrol-induced cell cycle arrest, apoptosis, and down-regulation of the Hsp90 client protein, epidermal growth factor receptor. | celastrol | heat shock protein 90 alpha family class A member 1 | Homo sapiens |
4 | Combined treatment of glioma cells with sulfasalazine and celastrol led to chemosensitization, as suggested by increased celastrol-induced cell cycle arrest, apoptosis, and down-regulation of the Hsp90 client protein, epidermal growth factor receptor. | celastrol | heat shock protein 90 alpha family class A member 1 | Homo sapiens |