Title : Dexamethasone reduces mitomycin C-related inflammatory cytokine expression without inducing further cell death in corneal fibroblasts.

Pub. Date : 2010 Jan-Feb

PMID : 20002897






2 Functional Relationships(s)
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Compound Name
Protein Name
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1 DEX dose dependently down-regulated basal and MMC-induced interleukin-8 and monocyte chemoattractant protein-1 mRNA expression and protein secretion. Dexamethasone C-C motif chemokine ligand 2 Homo sapiens
2 These suggested that DEX may inhibit MMC-induced interleukin-8 and monocyte chemoattractant protein-1 by up-regulating MKP-1 expression, which subsequently deactivated p38 and Jun N-terminal kinases activation. Dexamethasone C-C motif chemokine ligand 2 Homo sapiens