Title : A short, strong hydrogen bond in the active site of human carbonic anhydrase II.

Pub. Date : 2010 Jan 19

PMID : 20000378






2 Functional Relationships(s)
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1 The crystal structure of human carbonic anhydrase II (HCA II) obtained at 0.9 A resolution reveals that a water molecule, termed deep water, Dw, and bound in a hydrophobic pocket of the active site forms a short, strong hydrogen bond with the zinc-bound solvent molecule, a conclusion based on the observed oxygen-oxygen distance of 2.45 A. Water carbonic anhydrase 2 Homo sapiens
2 The crystal structure of human carbonic anhydrase II (HCA II) obtained at 0.9 A resolution reveals that a water molecule, termed deep water, Dw, and bound in a hydrophobic pocket of the active site forms a short, strong hydrogen bond with the zinc-bound solvent molecule, a conclusion based on the observed oxygen-oxygen distance of 2.45 A. Water carbonic anhydrase 2 Homo sapiens