Title : Enhancement effect of adenovirus-mediated antisense c-myc and caffeine on the cytotoxicity of cisplatin in osteosarcoma cell lines.

Pub. Date : 2009

PMID : 19996588






4 Functional Relationships(s)
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1 Enhancement effect of adenovirus-mediated antisense c-myc and caffeine on the cytotoxicity of cisplatin in osteosarcoma cell lines. Cisplatin MYC proto-oncogene, bHLH transcription factor Homo sapiens
2 Myc-AS or caffeine can enhance the cytotoxic effects of 2.0 and 5.0 microg/ml CDDP on MG-63 cells. Cisplatin MYC proto-oncogene, bHLH transcription factor Homo sapiens
3 Moreover, the significantly enhancing effect of the Myc-AS-caffeine combination on CDDP chemotherapy of MG-63 cells was not restricted to apoptosis but also decreased tumor cell proliferation in vitro. Cisplatin MYC proto-oncogene, bHLH transcription factor Homo sapiens
4 Myc-AS combined with caffeine can enhance apoptosis induction and chemotherapeutic effects of CDDP on osteosarcoma MG-63 cells. Cisplatin MYC proto-oncogene, bHLH transcription factor Homo sapiens