Title : Inhibition of Y-box binding protein-1 slows the growth of glioblastoma multiforme and sensitizes to temozolomide independent O6-methylguanine-DNA methyltransferase.

Pub. Date : 2009 Dec

PMID : 19996271






2 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Inhibition of Y-box binding protein-1 slows the growth of glioblastoma multiforme and sensitizes to temozolomide independent O6-methylguanine-DNA methyltransferase. Temozolomide Y-box binding protein 1 Homo sapiens
2 Importantly, inhibiting YB-1 enhanced temozolomide sensitivity in a manner that was independent of MGMT in models of adult and pediatric GBM. Temozolomide Y-box binding protein 1 Homo sapiens