Title : Inhibition of the Epstein-Barr virus lytic cycle by moronic acid.

Pub. Date : 2010 Mar

PMID : 19969023






2 Functional Relationships(s)
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1 Our immunoblotting and flow cytometry analyses find that moronic acid, found in galls of Rhus chinensis and Brazilian propolis, at 10microM inhibits the expression of Rta, Zta, and an EBV early protein, EA-D, after lytic induction with sodium butyrate. moronic acid collagen like tail subunit of asymmetric acetylcholinesterase Homo sapiens
2 Because the expression of Zta, EA-D and many EBV lytic genes depends on Rta, the treatment of P3HR1 cells with moronic acid substantially reduces the numbers of EBV particles produced by the cells after lytic induction. moronic acid collagen like tail subunit of asymmetric acetylcholinesterase Homo sapiens